Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875665 | 0.85 | DPP4 (0.50) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL29750499 | 0.81 | DPP4 (0.67) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL27996817 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL751142 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL29415456 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL751143 | 0.79 | DPP4 (0.65) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL28766330 | 0.78 | DPP4 (0.63) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL2807373 | 0.76 | DPP4 (0.61) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL31031060 | 0.76 | DPP4 (0.61) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL29569099 | 0.76 | DPP4 (0.61) | DPP4DPP9DPP8GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015386-A1 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | BHATNAGAR RAJENDRA SAHAI (US) | 2026-01-15 | — | — | US | disclosed |
| US-12325760-B2 | Inhibitors of NF kappa-B activity for treatment of diseases and disorders | BHATNAGAR RAJENDRA SAHAI (US) | 2025-06-10 | — | — | US | disclosed |
| US-20240180997-A1 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | BHATNAGAR RAJENDRA SAHAI (US) | 2024-06-06 | — | — | US | disclosed |
| US-20240083941-A1 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | BHATNAGAR RAJENDRA SAHAI (US) | 2024-03-14 | — | — | US | disclosed |
| US-11773135-B2 | Inhibitors of NF kappa-B activity for treatment of diseases and disorders | BHATNAGAR RAJENDRA SAHAI (US) | 2023-10-03 | — | — | US | disclosed |
| EP-4203988-A2 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | Bhatnagar, Rajendra, Sahai (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-114432423-A | NF for treating diseases and disorderskInhibitors of B activity | 拉金德拉·萨哈伊·巴特纳格尔 | 2022-05-06 | — | — | CN | disclosed |
| US-20220133837-A1 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | BHATNAGAR RAJENDRA SAHAI (US) | 2022-05-05 | — | — | US | disclosed |
| US-20220106359-A1 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | BHATNAGAR RAJENDRA SAHAI (US) | 2022-04-07 | — | — | US | disclosed |
| WO-2022047225-A2 | PEPTIDE INHIBITORS OF NF KAPPA B AND USE THEREOF IN TREATMENT OF COVID-19 AND INFLAMMATORY DISEASES | BHATNAGAR RAJENDRA SAHAI (US) | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015386-A1 | INHIBITORS OF NF KAPPA-B ACTIVITY FOR TREATMENT OF DISEASES AND DISORDERS | NFKBIA, NFRKB, NFKB1 | DPP4 2106/4885DPP9 793/4885DPP8 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.