Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616332 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL20348516 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL154510 | 0.80 | CYP11B1 (0.52) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL2334976 | 0.80 | CYP11B1 (0.52) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL10623849 | 0.79 | AR (0.46) | ALDH1A1HTTRECQLARPIK3CD | |
| SCHEMBL25443617 | 0.79 | CYP11B1 (0.51) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL6793277 | 0.79 | CYP11B1 (0.51) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL902429 | 0.79 | CYP11B1 (0.51) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL21893788 | 0.79 | CYP11B1 (0.51) | ALDH1A1HTTRECQLCYP11B1CYP11B2 | |
| SCHEMBL12461862 | 0.79 | CYP11B1 (0.51) | ALDH1A1HTTRECQLCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056252-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERGLYCEMIA IN TYPE-2 DIABETES | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-03-17 | — | — | WO | disclosed |