Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.89 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.89 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.89 |
| ▸ | UBA1 | P22314 | 1/20 | 0.89 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.89 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.89 |
| ▸ | RNMT | O43148 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 2/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18297457 | 1.00 | CA2 (0.89) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL23760337 | 0.94 | CA2 (1.00) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL18297434 | 0.94 | CA2 (1.00) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL29406144 | 0.94 | CA2 (1.00) | CA2NAE1UBA3UBA1SAE1 | |
| Hydrochloric Acid SCHEMBL18297575 | 0.94 | CA2 (0.99) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL18297670 | 0.92 | CA2 (0.88) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL29484005 | 0.91 | CA2 (1.00) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL18297530 | 0.91 | CA2 (1.00) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL20608753 | 0.91 | CA2 (0.73) | CA2NAE1UBA3UBA1SAE1 | |
| SCHEMBL18297439 | 0.91 | CA2 (0.85) | CA2NAE1UBA3UBA1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056252-A1 | COMPOSITIONS AND METHODS FOR TREATING HYPERGLYCEMIA IN TYPE-2 DIABETES | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2022-03-17 | — | — | WO | disclosed |