Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 3/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464181 | 0.89 | GRM7 (0.73) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL8225263 | 0.89 | GRM7 (0.73) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL25464184 | 0.89 | GRM7 (0.73) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL15189100 | 0.84 | GRM7 (0.68) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL6009184 | 0.82 | GRM7 (0.64) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL27904590 | 0.81 | GRM7 (0.62) | GRM7EPHX1LMNAGPR88TSHR | |
| SCHEMBL22873024 | 0.78 | EPHX2 (0.60) | GRM7LMNAGPR88CYP3A4HPGD | |
| SCHEMBL19200942 | 0.78 | GRM7 (1.00) | GRM7LMNARAB9A | |
| SCHEMBL19200544 | 0.78 | GRM7 (1.00) | GRM7LMNARAB9A | |
| SCHEMBL9260619 | 0.76 | EPHX1 (0.56) | GRM7EPHX1LMNAGPR88TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313234-B | Pyrazolo-triazolopyrimidine derivatives as A2A receptor antagonists | 百济神州有限公司 | 2022-04-29 | — | — | CN | disclosed |