Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448151 | 0.83 | ALDH1A1 (0.62) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL5448009 | 0.83 | KMT2A (0.79) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL5449585 | 0.82 | ALDH1A1 (0.67) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL25062693 | 0.80 | KMT2A (1.00) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL525757 | 0.80 | KMT2A (0.69) | KMT2AGAAALDH1A1POLBMEN1 | |
| Urea SCHEMBL27455873 | 0.79 | GAA (0.59) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL14096468 | 0.77 | ALDH1A1 (0.77) | KMT2AALDH1A1POLBMEN1SMN1; SMN2 | |
| SCHEMBL14096469 | 0.77 | ALDH1A1 (1.00) | KMT2AALDH1A1POLBMEN1SMN1; SMN2 | |
| SCHEMBL20010621 | 0.77 | KMT2A (0.60) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL19281517 | 0.77 | GAA (0.71) | KMT2AGAAALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |