Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 2/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251120 | 1.00 | KDM4E (1.00) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL9297638 | 0.87 | KDM4E (0.77) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL821844 | 0.84 | KDM4E (0.71) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL7798242 | 0.84 | KDM4E (0.72) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL38656393 | 0.82 | KDM4E (0.70) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL28542399 | 0.82 | KDM4E (0.70) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL30951916 | 0.81 | KDM4E (0.68) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL3117402 | 0.81 | KDM4E (0.68) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL13765760 | 0.81 | KDM4E (0.68) | KDM4ELMNAGRM5MAPK8MEN1 | |
| SCHEMBL12664038 | 0.81 | KDM4E (0.68) | KDM4ELMNAGRM5MAPK8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057932-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |
| WO-2022057928-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2022-03-24 | — | — | WO | disclosed |