Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.60 |
| ▸ | GRM5 | P41594 | 3/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500931 | 0.85 | P2RX7 (0.62) | KDM4ELMNAP2RX7GRM5ALDH1A1 | |
| SCHEMBL18246190 | 0.83 | P2RX7 (0.64) | KDM4ELMNAP2RX7GRM5ALDH1A1 | |
| SCHEMBL7798242 | 0.83 | KDM4E (0.72) | KDM4ELMNAGRM5MAPK8ALDH1A1 | |
| SCHEMBL9297638 | 0.82 | KDM4E (0.77) | KDM4ELMNAGRM5MAPK8ALDH1A1 | |
| SCHEMBL29049783 | 0.82 | P2RX7 (0.62) | KDM4ELMNAP2RX7GRM5ALDH1A1 | |
| SCHEMBL2251120 | 0.81 | KDM4E (1.00) | KDM4ELMNAGRM5MAPK8ALDH1A1 | |
| SCHEMBL29484609 | 0.81 | KDM4E (1.00) | KDM4ELMNAGRM5MAPK8ALDH1A1 | |
| SCHEMBL821844 | 0.80 | KDM4E (0.71) | KDM4ELMNAGRM5MAPK8ALDH1A1 | |
| SCHEMBL1142172 | 0.80 | P2RX7 (0.74) | KDM4ELMNAP2RX7ALDH1A1GAA | |
| SCHEMBL18519145 | 0.79 | P2RX7 (0.68) | KDM4ELMNAP2RX7ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176842-A1 | SUBSTITUTED ARYLSULFONAMIDES AS ANTIVIRAL AGENTS | AICURIS ANTI-INFECTIVE CURES GMBH (DE) | 2009-07-09 | — | — | US | disclosed |
| WO-2007101573-A1 | SUBSTITUTED ARYLSULFONAMIDES AS ANTIVIRAL AGENTS | AICURIS GMBH & CO. KG (DE) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176842-A1 | SUBSTITUTED ARYLSULFONAMIDES AS ANTIVIRAL AGENTS | TPMT, ARSA, TYMP | KDM4E 2391/4885LMNA 3748/4885P2RX7 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.