SCHEMBL29484960

SCHEMBL29484960

CC(C)C[C@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 13/20 0.67
▸ NMBR P28336 2/20 0.53
▸ GLP1R P43220 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484954 1.00 GRPR (0.67) GRPRNMBRGLP1R
SCHEMBL30816315 0.97 GRPR (0.63) GRPRNMBRGLP1R
SCHEMBL30398505 0.97 GRPR (0.64) GRPRNMBR
SCHEMBL27378954 0.96 GRPR (0.69) GRPRNMBR
SCHEMBL27379518 0.96 GRPR (0.69) GRPRNMBR
SCHEMBL30118082 0.95 GRPR (0.65) GRPRGLP1R
SCHEMBL25081963 0.95 GRPR (0.69) GRPRNMBR
SCHEMBL25081959 0.95 GRPR (0.69) GRPRNMBR
SCHEMBL24253292 0.95 GRPR (0.69) GRPRNMBR
SCHEMBL24253291 0.95 GRPR (0.69) GRPRNMBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025215527-A2 PHARMACEUTICAL COMBINATIONS AND USES THEREOF NOVARTIS AG (CH) 2025-10-16 — — WO disclosed
US-20250319214-A1 A NOVEL KIT FOR RADIOPHARMACEUTICAL PREPARATION OF A RADIOMETAL LABELED CHELATE-FUNCTIONALIZED TARGETING CONJUGATE Life Molecular Imaging Ltd. (GB) 2025-10-16 — — US disclosed
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-09-30 — — US disclosed
EP-4618991-A1 PHARMACEUTICAL COMBINATIONS AND USES THEREOF Novartis AG (CH) 2025-09-24 — — EP disclosed
US-20240197715-A1 PHARMACEUTICAL COMBINATIONS AND USES THEREOF NOVARTIS AG (CH) 2024-06-20 — — US disclosed
WO-2024105610-A1 PHARMACEUTICAL COMBINATIONS AND USES THEREOF NOVARTIS AG (CH) 2024-05-23 — — WO disclosed
EP-3909948-B1 BIFUNCTIONAL DO2PA DERIVATIVES, CHELATES WITH METALLIC CATIONS AND USE THEREOF CENTRE NAT RECH SCIENT (FR) 2024-02-28 — — EP disclosed
US-20220062446-A1 DUAL MODE 18F-LABELLED THERANOSTIC COMPOUNDS AND USES THEREOF PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427209-B2 Dual mode 18F-labelled theranostic compounds and uses thereof TFRC, SLC39A3, SLC39A14 GRPR 529/4885NMBR 261/4885GLP1R 873/4885
US-20240197715-A1 PHARMACEUTICAL COMBINATIONS AND USES THEREOF WRN, RECQL, BLM GRPR 2759/4885NMBR 3601/4885GLP1R 1636/4885
US-20220062446-A1 DUAL MODE 18F-LABELLED THERANOSTIC COMPOUNDS AND USES THEREOF TFRC, SLC39A3, SLC39A14 GRPR 529/4885NMBR 261/4885GLP1R 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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