Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 11/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023390 | 0.82 | BDKRB1 (0.54) | BDKRB1 | |
| SCHEMBL3615281 | 0.78 | BDKRB1 (0.62) | BDKRB1 | |
| SCHEMBL13213897 | 0.78 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL3030512 | 0.78 | BDKRB1 (0.54) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL3010080 | 0.77 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL3025046 | 0.77 | BDKRB1 (0.52) | BDKRB1 | |
| SCHEMBL3025041 | 0.77 | BDKRB1 (0.52) | BDKRB1 | |
| SCHEMBL3018282 | 0.77 | BDKRB1 (0.34) | BDKRB1 | |
| SCHEMBL13213899 | 0.76 | BDKRB1 (0.53) | BDKRB1 | |
| SCHEMBL3025468 | 0.74 | BDKRB1 (0.65) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |