Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 18/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021373 | 0.82 | BDKRB1 (0.47) | BDKRB1 | |
| SCHEMBL13214029 | 0.81 | BDKRB1 (0.44) | BDKRB1 | |
| SCHEMBL13213909 | 0.79 | BDKRB1 (0.42) | BDKRB1 | |
| SCHEMBL3031581 | 0.79 | BDKRB1 (0.48) | BDKRB1 | |
| SCHEMBL2948500 | 0.77 | MET (0.42) | BDKRB1 | |
| SCHEMBL13213908 | 0.77 | BDKRB1 (0.46) | BDKRB1 | |
| SCHEMBL13214038 | 0.71 | BDKRB1 (0.43) | BDKRB1 | |
| SCHEMBL17823722 | 0.71 | S1PR3 (0.42) | — | |
| SCHEMBL21725703 | 0.71 | S1PR3 (0.42) | — | |
| SCHEMBL29441073 | 0.71 | S1PR3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |