SCHEMBL2948503

SCHEMBL2948503

CCN(Cc1ccc(-c2cccc(F)c2C(=O)OC)cc1F)C(=O)NNC(=O)c1cncc(F)c1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2950595 0.81 BDKRB1 (0.60) BDKRB1
SCHEMBL2948506 0.81 BDKRB1 (0.58) BDKRB1
SCHEMBL2948509 0.76 BDKRB1 (0.58) BDKRB1
SCHEMBL2952519 0.76 BDKRB1 (0.57) BDKRB1
SCHEMBL2944724 0.72 BDKRB1 (0.46) BDKRB1
SCHEMBL2940473 0.70 BDKRB1 (0.72) BDKRB1
SCHEMBL6109422 0.70 BDKRB1 (0.72) BDKRB1
SCHEMBL2950597 0.70 BDKRB1 (0.72) BDKRB1
Hydrochloric Acid SCHEMBL5923244 0.69 BDKRB1 (0.71) BDKRB1
SCHEMBL5929278 0.69 BDKRB1 (0.76) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396301-A2 SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS Jerini AG (DE) 2011-12-21 EP disclosed
WO-2010091876-A2 SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS JERINI AG (DE) 2010-08-19 WO disclosed