Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950595 | 0.90 | BDKRB1 (0.60) | BDKRB1 | |
| SCHEMBL2944726 | 0.79 | BDKRB1 (0.56) | BDKRB1 | |
| SCHEMBL2943305 | 0.76 | FFAR1 (0.45) | BDKRB1LTB4R2 | |
| Hydrochloric Acid SCHEMBL2943097 | 0.75 | FFAR1 (0.44) | BDKRB1LTB4R2 | |
| SCHEMBL2948503 | 0.72 | BDKRB1 (0.50) | BDKRB1 | |
| SCHEMBL2944727 | 0.71 | BDKRB1 (0.58) | BDKRB1 | |
| SCHEMBL2946700 | 0.70 | BDKRB1 (0.49) | BDKRB1 | |
| Hydrochloric Acid SCHEMBL2951914 | 0.70 | BDKRB1 (0.49) | BDKRB1 | |
| SCHEMBL2950597 | 0.69 | BDKRB1 (0.72) | BDKRB1 | |
| SCHEMBL2940473 | 0.68 | BDKRB1 (0.72) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396301-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091876-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2010-08-19 | — | — | WO | disclosed |