SCHEMBL2948522

SCHEMBL2948522

CCCCCc1nc2ccccc2n1S

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 3/20 0.53
GLA P06280 1/20 0.52
MAPT P10636 2/20 0.50
ATM Q13315 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
AGTR1 P30556 1/20 0.50
AGTR2 P50052 1/20 0.50
LMNA P02545 3/20 0.49
TSHR P16473 1/20 0.49
KDM4E B2RXH2 1/20 0.48
TLR8 Q9NR97 2/20 0.48
TP53 P04637 1/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
APEX1 P27695 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17933567 0.82 MAPT (0.72) TLR7GLAMAPTSMN1; SMN2LMNA
SCHEMBL6142135 0.81 MEN1 (0.66) GLAMAPTAGTR1AGTR2LMNA
SCHEMBL11395129 0.81 MAPT (0.75) TLR7GLAMAPTSMN1; SMN2AGTR1
SCHEMBL2361056 0.79 TP53 (0.69) GLAMAPTSMN1; SMN2LMNATLR8
SCHEMBL10325213 0.79 MEN1 (0.64) TLR7GLAMAPTAGTR1AGTR2
SCHEMBL10818398 0.78 POLB (0.54) TLR7GLAMAPTATMSMN1; SMN2
SCHEMBL28878994 0.78 LMNA (0.67) GLAMAPTSMN1; SMN2AGTR1AGTR2
SCHEMBL28879019 0.78 LMNA (0.67) GLAMAPTSMN1; SMN2AGTR1AGTR2
SCHEMBL29968953 0.78 LMNA (0.67) GLAMAPTSMN1; SMN2AGTR1AGTR2
SCHEMBL28879087 0.78 LMNA (0.67) GLAMAPTSMN1; SMN2AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1886759-B1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEM (JP) 2016-10-05 EP disclosed
US-7754105-B2 Water-soluble preflux and usage of the same SHIKOKU CHEMICALS CORPORATION (JP) 2010-07-13 US disclosed
US-20080318070-A1 Water-Soluble Preflux and Usage of the Same SHIKOKU CHEMICALS CORPORATION (JP) 2008-12-25 US disclosed
EP-1886759-A1 WATER-SOLUBLE PREFLUX AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2008-02-13 EP disclosed