Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Broxyquinoline SCHEMBL5712599 | 1.00 | KDM4E (0.61) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL9976765 | 0.78 | KDM4E (0.66) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| Broxyquinoline SCHEMBL30485535 | 0.76 | KDM4E (1.00) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL14212918 | 0.76 | KDM4E (0.62) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| Broxyquinoline SCHEMBL29607319 | 0.76 | KDM4E (1.00) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL2204811 | 0.76 | HSP90AA1 (0.62) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| Broxyquinoline SCHEMBL115293 | 0.76 | KDM4E (1.00) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL1714224 | 0.76 | KMT2A (0.58) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| Broxyquinoline SCHEMBL22734870 | 0.74 | KDM4E (0.96) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| Broxyquinoline SCHEMBL31157810 | 0.74 | KDM4E (0.96) | KDM4EHSP90AA1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114141971-A | Organic electroluminescent device containing phenanthryl triarylamine compound and application thereof | 江苏三月科技股份有限公司 | 2022-03-04 | — | — | CN | disclosed |