Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 1.00 |
| ▸ | BCHE | P06276 | 10/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 1.00 |
| ▸ | BACE1 | P56817 | 2/20 | 1.00 |
| ▸ | GABRP | O00591 | 1/20 | 1.00 |
| ▸ | GABRD | O14764 | 1/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 1.00 |
| ▸ | GABRB1 | P18505 | 1/20 | 1.00 |
| ▸ | GABRG2 | P18507 | 1/20 | 1.00 |
| ▸ | GABRB3 | P28472 | 1/20 | 1.00 |
| ▸ | GABRA5 | P31644 | 1/20 | 1.00 |
| ▸ | GABRA3 | P34903 | 1/20 | 1.00 |
| ▸ | GABRA2 | P47869 | 1/20 | 1.00 |
| ▸ | GABRB2 | P47870 | 1/20 | 1.00 |
| ▸ | GABRA4 | P48169 | 1/20 | 1.00 |
| ▸ | GABRE | P78334 | 1/20 | 1.00 |
| ▸ | GABRA6 | Q16445 | 1/20 | 1.00 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 1.00 |
| ▸ | GABRG3 | Q99928 | 1/20 | 1.00 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24164216 | 1.00 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL15168191 | 1.00 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL12059555 | 1.00 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| Hydrochloric Acid SCHEMBL29711388 | 0.99 | BCHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL24000133 | 0.99 | BCHE (0.97) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL29869028 | 0.97 | ACHE (0.95) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL1532498 | 0.97 | ACHE (0.95) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL13480729 | 0.96 | BCHE (0.92) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL5945380 | 0.94 | ACHE (1.00) | ACHEBCHEAPPBACE1GABRP | |
| SCHEMBL7674463 | 0.94 | BCHE (0.88) | ACHEBCHEAPPBACE1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| US-20250017942-A1 | Prevention and treatment of osteoarticular diseases by inhibiting acetylcholinesterase | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2025-01-16 | — | — | US | disclosed |
| WO-2023205788-A1 | ENHANCED HAMMERHEAD RIBOZYMES AND METHODS OF USE | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2023-10-26 | — | — | WO | disclosed |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-4208257-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | Collaborations Pharmaceuticals, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2023070351-A1 | PREVENTION AND TREATMENT OF OSTEOARTICULAR DISEASES BY INHIBITING ACETYLCHOLINESTERASE | 香港理工大学 | 2023-05-04 | — | — | WO | disclosed |
| CN-116019915-A | Prevention and treatment of bone joint diseases by inhibition of acetylcholinesterase | 香港理工大学 | 2023-04-28 | — | — | CN | disclosed |
| WO-2022161556-A1 | TACRINE DERIVATIVES POSSESSING DUAL ACTIVITY AND THEIR USE | FAKULTNI NEMOCNICE HRADEC KRALOVE (CZ) | 2022-08-04 | — | — | WO | disclosed |
| WO-2022061019-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017942-A1 | Prevention and treatment of osteoarticular diseases by inhibiting acetylcholinesterase | ACHE, BCHE, CHAT | ACHE 1/4885BCHE 2/4885APP 1072/4885 |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | ACHE, BCHE, ACE | ACHE 1/4885BCHE 2/4885APP 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.