SCHEMBL2948714

SCHEMBL2948714

CCCCCCCC/C=C\CCCCCCC(C)C1=NCCN1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.42
MAOB P27338 3/20 0.42
NISCH Q9Y2I1 3/20 0.42
FAAH O00519 2/20 0.36
TRPV1 Q8NER1 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787845 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL186179 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL3451044 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL3682171 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL11681324 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL10948420 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL6292173 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL6292157 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL10491842 0.92 NISCH (0.47) MAOAMAOBNISCHHTR1AADRA2A
SCHEMBL10628299 0.85 FFAR1 (0.40) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130130953-A1 WATER RESISTANT GREASE COMPOSITION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-05-23 US claimed
US-10676689-B2 Grease compositions for low temperature operation EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-09 US disclosed
US-20190203150-A1 GREASE COMPOSITIONS FOR LOW TEMPERATURE OPERATION EXXONMOBIL RES & ENG CO (US) 2019-07-04 US disclosed
EP-2776541-A1 WATER RESISTANT GREASE COMPOSITION ExxonMobil Research and Engineering Company (US) 2014-09-17 EP disclosed
US-20130130953-A1 WATER RESISTANT GREASE COMPOSITION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-05-23 US disclosed
WO-2013070588-A1 WATER RESISTANT GREASE COMPOSITION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-05-16 WO disclosed
US-7749523-B2 Emollient skin conditioning cream and method CRABTREE & EVELYN, LTD. (US) 2010-07-06 US disclosed
US-20030133900-A1 Emollient skin conditioning cream and method MAYBANK INVESTMENT BANK BERHAD (MY) 2003-07-17 US disclosed
WO-2003026607-A2 EMOLLIENT SKIN CONDITIONING CREAM AND METHOD CRABTREE & EVELYN, LTD. (US) 2003-04-03 WO disclosed
US-3954647-A 1-HYDROXYETHYL-2-FATTY ACID IMIDAZOLINE HYDROCARBON OR HALOHYDROCARBON SOLVENT ANSCOTT CHEMICAL INDUSTRIES, INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030133900-A1 Emollient skin conditioning cream and method CUTA, CD69, C9 MAOA 2404/4885MAOB 3187/4885NISCH 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.