Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959954 | 1.00 | TLR8 (0.42) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL2748326 | 0.90 | TLR8 (0.43) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL29576809 | 0.90 | TLR8 (0.43) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL15960732 | 0.83 | TLR8 (0.52) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL22959955 | 0.83 | ESR1 (0.39) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL29915216 | 0.83 | TLR8 (0.39) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL12497089 | 0.83 | TLR8 (0.39) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL6004219 | 0.83 | KMT5B (0.50) | TLR8AXLPRKCIMAPTHSD17B10 | |
| SCHEMBL15079348 | 0.79 | ESR1 (0.39) | TLR8AXLPRKCIMAPTGAA | |
| SCHEMBL382814 | 0.79 | SRC (0.48) | EGFRFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206883-A | Oxopyridine fused ring derivative and pharmaceutical composition comprising the same | 伟迈可生物有限公司 | 2022-03-18 | — | — | CN | disclosed |