SCHEMBL29487308

SCHEMBL29487308

CO[Si](CCCOC(=O)/C=C\C(=O)O)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.61
ATM Q13315 1/20 0.48
MAPT P10636 2/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 2/20 0.34
HPGD P15428 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALOX5 P09917 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AKR1B10 O60218 1/20 0.33
AKR1B1 P15121 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107870 0.93 ATM (0.55) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL108806 0.93 ATM (0.55) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL107869 0.93 ATM (0.55) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1904077 0.91 ATM (0.53) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1900444 0.91 ATM (0.53) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL17918206 0.89 ATM (0.52) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7096201 0.88 ATM (0.50) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL7096198 0.88 ATM (0.50) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL16804272 0.86 ATM (0.48) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL12384955 0.86 ATM (0.48) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250218775-A1 MATERIALS AND METHODS FOR FORMING PATTERNED MASK ON SUBSTRATE GEMINATIO, INC. 2025-07-03 US disclosed
US-20250216790-A1 MATERIALS AND METHODS FOR FORMING PATTERNED MASK ON SUBSTRATE GEMINATIO, INC., 2025-07-03 US disclosed
EP-2665756-B1 METHOD FOR PRODUCING SILYL-FUNCTIONALIZED POLYOLEFINS AND SILYL-FUNCTIONALIZED POLYOLEFINS WITH SILYL MONOMER INCORPORATION DOW SILICONES CORP (US) 2022-03-30 EP disclosed