Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096198 | 1.00 | ATM (0.50) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL107870 | 0.94 | ATM (0.55) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL107869 | 0.94 | ATM (0.55) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL108806 | 0.94 | ATM (0.55) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL1904077 | 0.93 | ATM (0.53) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1900444 | 0.93 | ATM (0.53) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL17918206 | 0.91 | ATM (0.52) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL29487308 | 0.88 | HCAR2 (0.61) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL16804272 | 0.88 | ATM (0.48) | ATMHCAR2KEAP1NFE2L2MAPT | |
| SCHEMBL12384955 | 0.88 | ATM (0.48) | ATMHCAR2KEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991698-B1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-10-24 | — | — | EP | disclosed |
| US-6515043-B2 | Surface treatment of filler | CROMPTON CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6395856-B1 | CURABLE POLYSILOXANES FOR PROTECTIVE COATINGS FOR WIRES | CROMPTON CORPORATION | 2002-05-28 | — | — | US | disclosed |
| US-20010021761-A1 | Silicone oligomers with heigher alkoxy groups | MOMENTIVE PERFORMANCE MATERIALS INC. | 2001-09-13 | — | — | US | disclosed |
| US-6207783-B1 | UNDERGROUND INSULATION | CROMPTON CORPORATION | 2001-03-27 | — | — | US | disclosed |
| EP-0991698-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | CK WITCO CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999054386-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | WITCO CORPORATION (US) | 1999-10-28 | — | — | WO | disclosed |