Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940791 | 1.00 | HTR2C (0.40) | HTR2CHTR2BTRPV3IDO1PDE10A | |
| SCHEMBL15722917 | 0.91 | HTR2C (0.36) | HTR2CHTR2BTRPV3IDO1PDE10A | |
| SCHEMBL20011091 | 0.89 | TRPV3 (0.39) | TRPV3IDO1PDE10AOPRL1 | |
| SCHEMBL31067203 | 0.87 | KDM1A (0.38) | HTR2CHTR2BTRPV3IDO1PDE10A | |
| SCHEMBL30796735 | 0.84 | PDE10A (0.34) | TRPV3IDO1PDE10ANOS3NOS1 | |
| SCHEMBL27448900 | 0.84 | PDE10A (0.34) | TRPV3IDO1PDE10ANOS3NOS1 | |
| SCHEMBL22857372 | 0.79 | TRPV3 (0.37) | TRPV3IDO1PDE10ASLC6A4SLC6A3 | |
| SCHEMBL12906947 | 0.79 | PDE10A (0.33) | TRPV3IDO1PDE10A | |
| SCHEMBL10091334 | 0.79 | PDE10A (0.36) | TRPV3IDO1PDE10AOPRL1 | |
| SCHEMBL27266235 | 0.79 | PDE10A (0.39) | PDE10AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |