Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940779 | 1.00 | APP (0.33) | APPBACE1BTKSUV39H2KDM4E | |
| SCHEMBL20010782 | 0.88 | MAPK14 (0.33) | BTKSUV39H2KDM4EMEN1USP2 | |
| SCHEMBL20011090 | 0.87 | SUV39H2 (0.32) | BTKSUV39H2IKBKETBK1 | |
| SCHEMBL22857371 | 0.79 | TBK1 (0.32) | BTKSUV39H2IKBKETBK1 | |
| SCHEMBL24497739 | 0.79 | IKBKE (0.31) | SUV39H2IKBKETBK1 | |
| SCHEMBL6638540 | 0.78 | FFAR1 (0.38) | KDM4EALDH1A1MAPT | |
| SCHEMBL2489342 | 0.77 | BTK (0.33) | BACE1BTKSUV39H2MAPTIKBKE | |
| SCHEMBL1528269 | 0.77 | SUV39H2 (0.33) | BTKSUV39H2IKBKETBK1 | |
| SCHEMBL20010988 | 0.77 | SUV39H2 (0.40) | BTKSUV39H2ALDH1A1LMNAMAPT | |
| SCHEMBL11917083 | 0.77 | CA1 (0.33) | APPBACE1CNR2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |