Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012638 | 1.00 | SLC22A12 (0.39) | SLC22A12POLBTDP1NFE2L2KMO | |
| SCHEMBL14333928 | 0.83 | S1PR3 (0.42) | SLC22A12NFE2L2S1PR3CA7CA9 | |
| SCHEMBL148901 | 0.78 | AAK1 (0.44) | KMOSORT1AAK1ASPH | |
| SCHEMBL25068658 | 0.78 | POLB (0.42) | POLBTDP1KMOCA12CA1 | |
| SCHEMBL7042463 | 0.78 | CA12 (0.57) | POLBTDP1KMOCA12CA1 | |
| SCHEMBL29877864 | 0.77 | ASPH (0.41) | NFE2L2KMOSORT1ASPH | |
| SCHEMBL15774523 | 0.77 | KDM5A (0.37) | KMOSORT1AAK1 | |
| SCHEMBL1699267 | 0.76 | NAPRT (0.43) | KMOS1PR3SORT1ASPH | |
| SCHEMBL30639556 | 0.76 | POLB (0.43) | POLBTDP1CA12CA1CA2 | |
| SCHEMBL12794738 | 0.76 | POLB (0.43) | POLBTDP1KMOCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |
| CN-114206856-A | Anti-malarial hexahydropyrimidine analogues | UCB生物制药有限责任公司 | 2022-03-18 | — | — | CN | disclosed |