SCHEMBL29489079

SCHEMBL29489079

Brc1ccc(-c2ccc(-c3cccc4c3sc3ccccc34)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.59
PARP14 Q460N5 1/20 0.44
GPR3 P46089 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
PRKDC P78527 4/20 0.40
SLC6A3 Q01959 1/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
RAB9A P51151 2/20 0.36
KMT2A Q03164 2/20 0.36
LIMK1 P53667 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10044990 1.00 ALOX5 (0.59) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL2597559 0.98 ALOX5 (0.60) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL21428316 0.95 ALOX5 (0.57) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL16282334 0.91 ALOX5 (0.51) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL15893248 0.91 ALOX5 (0.68) ALOX5PARP14GPR3ALDH1A1PRKDC
SCHEMBL17383080 0.91 ALOX5 (0.61) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL28930465 0.90 ALOX5 (0.52) ALOX5PARP14GPR3ALDH1A1MAPK1
Biphenyl-4-Amine SCHEMBL18209933 0.90 ALOX5 (0.50) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL12925528 0.90 ALOX5 (0.52) ALOX5PARP14GPR3ALDH1A1MAPK1
SCHEMBL21152361 0.89 ALOX5 (0.70) ALOX5PARP14GPR3ALDH1A1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436940-B Compounds and methods of synthesis 株式会社半导体能源研究所 2025-03-28 CN disclosed
CN-114436940-A Compound and synthesis method 株式会社半导体能源研究所 2022-05-06 CN disclosed
CN-108137565-B Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2022-03-08 CN disclosed