Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20358130 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL29427926 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL17633849 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL8765342 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL214110 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL20840679 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL7284649 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL4612051 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL30563642 | 0.85 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAP2RX4MEN1KMT2A | |
| SCHEMBL4742545 | 0.85 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAP2RX4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3972652-A1 | ANTIBODY-DRUG CONJUGATES AND THEIR USE IN THERAPY | Mc SAF (FR) | 2022-03-30 | — | — | EP | disclosed |