SCHEMBL29489291

CSCC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](C)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.59

▸	CCKBR	P32239	8/20	0.54

▸	NPY5R	Q15761	3/20	0.52

▸	NPY1R	P25929	2/20	0.52

▸	NPY4R	P50391	2/20	0.52

▸	IL23R	Q5VWK5	1/20	0.52

▸	APC	P25054	1/20	0.51

▸	RAMP3	O60896	1/20	0.50

▸	CALCR	P30988	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30524359	0.88	TFPI (0.61)	TFPICCKBRNPY5RNPY1RNPY4R
SCHEMBL30429239	0.87	TFPI (0.62)	TFPINPY5RNPY1RNPY4R
SCHEMBL29596291	0.87	TFPI (0.66)	TFPIRAMP3CALCR
SCHEMBL30310937	0.86	TFPI (0.58)	TFPINPY5RNPY1RNPY4R
SCHEMBL29594800	0.85	TFPI (0.62)	TFPINPY5RNPY1RNPY4RRAMP3
SCHEMBL30883227	0.85	TFPI (0.56)	TFPINPY5RNPY1RNPY4R
SCHEMBL30139094	0.85	PTH1R (0.57)	TFPICCKBR
SCHEMBL30904843	0.85	NPY4R (0.58)	TFPICCKBRNPY5RNPY1RNPY4R
SCHEMBL23273225	0.84	TFPI (0.54)	TFPICCKBR
SCHEMBL29498759	0.84	TFPI (0.55)	TFPINPY5RNPY1RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-113347994-B	Treatment and prevention of cancer using HER3 antigen binding molecules	蜂鸟生物科技私人有限公司	2022-09-23	—	—	CN	disclosed
CN-114751983-A	HER3 antigen binding molecules	蜂鸟生物科技私人有限公司	2022-07-15	—	—	CN	disclosed
CN-112513095-B	HER3 antigen binding molecules	蜂鸟生物科技控股有限公司	2022-03-08	—	—	CN	disclosed