Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 4/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862466 | 1.00 | HDAC1 (0.35) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29490248 | 0.86 | RAD52 (0.37) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL22862946 | 0.86 | RAD52 (0.37) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL24704178 | 0.84 | HDAC1 (0.35) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29490233 | 0.84 | HDAC1 (0.35) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29490229 | 0.84 | MAPT (0.35) | MAT2A | |
| SCHEMBL22862712 | 0.79 | HDAC3 (0.33) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL29490245 | 0.79 | HDAC3 (0.33) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL22862469 | 0.77 | CYP11B1 (0.39) | DPP4PDE10A | |
| SCHEMBL22862548 | 0.77 | POLB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |