Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862481 | 0.87 | MAPT (0.35) | RAD52MAPTKMT2ACYP19A1CYP1A2 | |
| SCHEMBL29490307 | 0.85 | RAD52 (0.43) | RAD52KMT2ACYP19A1TUBB4ATUBB | |
| SCHEMBL29490203 | 0.85 | MAPT (0.37) | RAD52MAPTKMT2ACYP19A1TUBB4A | |
| SCHEMBL22862947 | 0.83 | RAD52 (0.43) | RAD52TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29490308 | 0.83 | RAD52 (0.43) | RAD52TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22862594 | 0.78 | MAPT (0.40) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29490229 | 0.76 | MAPT (0.35) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24704321 | 0.72 | POLB (0.36) | RAD52KMT2ACYP19A1CYP1A2CYP2C9 | |
| SCHEMBL29490189 | 0.72 | POLB (0.36) | RAD52KMT2ACYP19A1CYP1A2CYP2C9 | |
| SCHEMBL22862462 | 0.72 | CYP11B1 (0.46) | RAD52ALDH1A1MAPK1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |