Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490229 | 0.87 | MAPT (0.35) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29490276 | 0.85 | NR1I2 (0.38) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29490216 | 0.85 | RAD52 (0.42) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22862594 | 0.84 | MAPT (0.40) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22862946 | 0.83 | RAD52 (0.37) | RAD52 | |
| SCHEMBL29490248 | 0.83 | RAD52 (0.37) | RAD52 | |
| SCHEMBL22862481 | 0.76 | MAPT (0.35) | MAPTKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22862432 | 0.73 | MAPK14 (0.42) | MAPTALDH1A1RAD52MAPK1POLB | |
| SCHEMBL29490284 | 0.73 | MAPK14 (0.42) | MAPTALDH1A1RAD52MAPK1POLB | |
| SCHEMBL29490207 | 0.72 | ALDH1A1 (0.36) | KMT2ACYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |