Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | TNF | P01375 | 1/20 | 0.76 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 13/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490321 | 1.00 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862834 | 1.00 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862471 | 1.00 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862425 | 1.00 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862473 | 0.88 | RAB9A (0.78) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862863 | 0.88 | RAB9A (0.78) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862865 | 0.86 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862444 | 0.86 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862521 | 0.86 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS | |
| SCHEMBL22862813 | 0.86 | RAB9A (0.76) | RAB9ATNFNOD1EGFRFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |