Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 4/20 | 0.35 |
| ▸ | PDE1A | P54750 | 3/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862855 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL29490177 | 0.96 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL22862856 | 0.96 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL22862779 | 0.86 | TRIM24 (0.40) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL29490310 | 0.86 | TRIM24 (0.42) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL22862638 | 0.86 | TRIM24 (0.42) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL22862953 | 0.86 | TRIM24 (0.42) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL29490202 | 0.86 | TRIM24 (0.42) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL24704281 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2TSHRL3MBTL1LMNAHTT | |
| SCHEMBL22862567 | 0.78 | CSF1R (0.36) | LMNAHTTNTRK1CSF1RNTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |