Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | UBE2N | P61088 | 2/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | BRD1 | O95696 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490310 | 0.87 | TRIM24 (0.42) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862779 | 0.87 | TRIM24 (0.40) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862638 | 0.87 | TRIM24 (0.42) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL29490202 | 0.87 | TRIM24 (0.42) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862953 | 0.87 | TRIM24 (0.42) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862855 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL29490249 | 0.83 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862856 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL29490177 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2L3MBTL1TSHRLMNAHTT | |
| SCHEMBL22862915 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1TSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | BAX, TMBIM6, BCL2 | SMN1; SMN2 2633/4885L3MBTL1 241/4885TSHR 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.