Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 12/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862683 | 1.00 | EGFR (0.36) | EGFRKDRPDGFRBSOS1NPC1 | |
| SCHEMBL29490277 | 0.92 | NPC1 (0.33) | EGFRKDRSOS1NPC1POLB | |
| SCHEMBL22862606 | 0.92 | NPC1 (0.33) | EGFRKDRSOS1NPC1POLB | |
| SCHEMBL24704616 | 0.90 | SOS1 (0.35) | SOS1 | |
| SCHEMBL29490306 | 0.83 | EGFR (0.46) | EGFRKDRPDGFRBSOS1 | |
| SCHEMBL22862554 | 0.83 | EGFR (0.46) | EGFRKDRPDGFRBSOS1 | |
| SCHEMBL22862605 | 0.82 | CTNNB1 (0.45) | EGFRSOS1 | |
| SCHEMBL29490271 | 0.82 | CTNNB1 (0.45) | EGFRSOS1 | |
| SCHEMBL22862676 | 0.81 | SMN1; SMN2 (0.36) | SOS1NPC1POLBRAB9A | |
| SCHEMBL29490179 | 0.81 | SMN1; SMN2 (0.36) | SOS1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |