Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 8/20 | 0.33 |
| ▸ | KRAS | P01116 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862676 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9APOLBKMT2A | |
| SCHEMBL29490271 | 0.84 | CTNNB1 (0.45) | SOS1KRAS | |
| SCHEMBL22862605 | 0.84 | CTNNB1 (0.45) | SOS1KRAS | |
| SCHEMBL22862702 | 0.83 | LDHA (0.36) | SOS1IDH1LDHAMAPTNPSR1 | |
| SCHEMBL22862718 | 0.81 | KRAS (0.42) | SMN1; SMN2RAB9AKMT2ASOS1KRAS | |
| SCHEMBL38653314 | 0.81 | KRAS (0.42) | SMN1; SMN2RAB9AKMT2ASOS1KRAS | |
| SCHEMBL29490316 | 0.81 | EGFR (0.36) | NPC1RAB9APOLBSOS1 | |
| SCHEMBL22862683 | 0.81 | EGFR (0.36) | NPC1RAB9APOLBSOS1 | |
| SCHEMBL22862634 | 0.80 | AKR1C3 (0.35) | POLBKMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL22862580 | 0.78 | IDH1 (0.42) | NPC1RAB9AKMT2APKMIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |