Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862666 | 1.00 | GAA (0.50) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL22862669 | 0.89 | HSD17B10 (0.43) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL29490299 | 0.89 | HSD17B10 (0.43) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL22862541 | 0.84 | GAA (0.47) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL29490204 | 0.84 | GAA (0.47) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL4249681 | 0.83 | HSD17B10 (0.50) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL14852094 | 0.79 | DRD2 (0.45) | GAAHSD17B10ALDH1A1KMT2ADRD2 | |
| SCHEMBL14722568 | 0.78 | HSD17B10 (0.42) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL24463038 | 0.75 | GAA (0.50) | GAAHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL15205213 | 0.75 | GAA (0.50) | GAAHSD17B10ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |