SCHEMBL29490404

SCHEMBL29490404

Brc1ccc(-c2cccc3ccccc23)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.52
DNMT1 P26358 1/20 0.44
ALDH1A1 P00352 4/20 0.42
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
CYP2A6 P11509 3/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
CYP1B1 Q16678 2/20 0.40
PTPN1 P18031 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALPL P05186 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL947346 1.00 CYP1A2 (0.52) CYP1A2DNMT1ALDH1A1CA12CA1
SCHEMBL16792034 0.92 CA12 (0.53) CYP1A2CA12CA1CA2CA9
SCHEMBL16683257 0.90 CYP1A2 (0.45) CYP1A2DNMT1ALDH1A1CA12CA1
SCHEMBL15158529 0.90 CYP1A2 (0.47) CYP1A2DNMT1ALDH1A1CA12CA1
SCHEMBL20598536 0.90 CYP1A2 (0.61) CYP1A2DNMT1ALDH1A1TSHRHSD17B10
SCHEMBL13631978 0.85 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1
SCHEMBL13632075 0.85 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1
SCHEMBL13631896 0.85 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1
SCHEMBL623432 0.85 CYP1A2 (0.47) CYP1A2ALDH1A1CYP1B1
SCHEMBL6077039 0.85 ALDH1A1 (0.56) CYP1A2DNMT1ALDH1A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4222790-A1 COMPOUNDS FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2023-08-09 EP disclosed
EP-4222792-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2023-08-09 EP disclosed
CN-116508417-A Compounds useful for structuring functional layers of organic electroluminescent devices 默克专利有限公司 2023-07-28 CN disclosed
CN-116250386-A Compounds for structuring functional layers of organic electroluminescent devices 默克专利有限公司 2023-06-09 CN disclosed
CN-114628616-A Light-emitting device and amine compound for light-emitting device 三星显示有限公司 2022-06-14 CN disclosed
WO-2022069422-A1 COMPOUNDS FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-04-07 WO disclosed
WO-2022069421-A1 COMPOUNDS THAT CAN BE USED FOR STRUCTURING FUNCTIONAL LAYERS OF ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-04-07 WO disclosed