Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 16/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22608426 | 1.00 | KMO (0.47) | KMOHAO1CHEK2SCN9APSD | |
| SCHEMBL22815844 | 0.94 | KMO (0.53) | KMOHAO1CHEK2SCN9A | |
| SCHEMBL22608428 | 0.86 | CHEK2 (0.41) | KMOHAO1CHEK2SCN9APSD | |
| SCHEMBL23294463 | 0.82 | HAO1 (0.53) | HAO1 | |
| SCHEMBL22815840 | 0.79 | CYP1A2 (0.48) | KMOHAO1CHEK2SCN9A | |
| SCHEMBL22608565 | 0.79 | USP7 (0.48) | HAO1 | |
| SCHEMBL22608623 | 0.78 | KMO (0.45) | KMOHAO1 | |
| SCHEMBL29490706 | 0.78 | KMO (0.45) | KMOHAO1 | |
| SCHEMBL22608235 | 0.77 | KMO (0.48) | KMOHAO1 | |
| SCHEMBL23294550 | 0.76 | HAO1 (0.50) | HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986863-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BioMarin Pharmaceutical Inc. (US) | 2022-04-27 | — | — | EP | disclosed |
| CN-114258390-A | Glycolate oxidase inhibitors for disease treatment | 生物马林药物股份有限公司 | 2022-03-29 | — | — | CN | disclosed |