Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490904 | 0.93 | HDAC6 (0.45) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL22745967 | 0.92 | HDAC6 (0.53) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL29490855 | 0.91 | HDAC6 (0.56) | HDAC6GRIN1GRIN2BHDAC1PARG | |
| SCHEMBL31192570 | 0.91 | HDAC6 (0.47) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL22716843 | 0.91 | HDAC6 (0.47) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL22746065 | 0.90 | HDAC6 (0.46) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL29490916 | 0.89 | GRIN1 (0.48) | HDAC6GRIN1GRIN2BHDAC1 | |
| SCHEMBL29490790 | 0.88 | HDAC6 (0.43) | HDAC6GRIN1GRIN2BHDAC1PARG | |
| SCHEMBL22745939 | 0.88 | HDAC6 (0.43) | HDAC6GRIN1GRIN2BHDAC1PARG | |
| SCHEMBL22745862 | 0.88 | HDAC6 (0.45) | HDAC6GRIN1GRIN2BHDAC1PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12440484-B2 | 1,3,4-oxadiazole homophthalimide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORPORATION (KR) | 2025-10-14 | — | — | US | disclosed |
| US-20230079386-A1 | 1,3,4-OXADIAZOLE HOMOPHTHALIMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORPORATION (KR) | 2023-03-16 | — | — | US | disclosed |
| EP-3976602-A1 | 1,3,4-OXADIAZOLE HOMOPHTHALIMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079386-A1 | 1,3,4-OXADIAZOLE HOMOPHTHALIMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC1, HDAC11, HDAC3 | HDAC6 4/4885GRIN1 690/4885GRIN2B 821/4885 |
| US-12440484-B2 | 1,3,4-oxadiazole homophthalimide derivative compounds as histone deacetylase 6 inhibitor, and the pharmaceutical composition comprising the same | HDAC1, HDAC11, HDAC3 | HDAC6 4/4885GRIN1 690/4885GRIN2B 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.