SCHEMBL31192570

SCHEMBL31192570

Cn1c(=O)n(Cc2ccc(-c3nnc(C(F)F)o3)cn2)c2ccc(-c3ccncc3)cc21

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 8/20 0.47
GRIN1 Q05586 11/20 0.47
GRIN2B Q13224 11/20 0.47
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22716843 1.00 HDAC6 (0.47) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL29490904 0.91 HDAC6 (0.45) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL28696647 0.91 HDAC6 (0.58) HDAC6GRIN1GRIN2B
SCHEMBL29504267 0.91 HDAC6 (0.58) HDAC6GRIN1GRIN2B
SCHEMBL29490804 0.91 HDAC6 (0.45) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL29504524 0.89 HDAC6 (0.44) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL28706733 0.89 HDAC1 (0.44) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL28695810 0.89 HDAC6 (0.44) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL29504350 0.89 HDAC1 (0.44) HDAC6GRIN1GRIN2BHDAC1
SCHEMBL22724987 0.88 HDAC6 (0.44) HDAC6GRIN1GRIN2BHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976604-B1 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2026-01-21 EP disclosed
CN-113924296-B 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same 株式会社 钟根堂 2024-09-17 CN disclosed