SCHEMBL29492091

SCHEMBL29492091

CCOc1ccc(-n2nc3ccc(Cl)cc3n2)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.46
MEN1 O00255 7/20 0.46
NPC1 O15118 4/20 0.46
PKM P14618 1/20 0.46
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 3/20 0.41
GAA P10253 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATM Q13315 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
MAPT P10636 7/20 0.39
TP53 P04637 2/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9639272 1.00 KMT2A (0.46) KMT2AMEN1NPC1PKMRAB9A
SCHEMBL29492032 0.90 PDE2A (0.41) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL17940503 0.90 PDE2A (0.41) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL9639345 0.90 DHODH (0.42) KMT2AMEN1NPC1PKMRAB9A
SCHEMBL9747646 0.87 NR5A1 (0.45) THRB
SCHEMBL7787935 0.87 NR5A1 (0.45) THRB
SCHEMBL8070225 0.87 ADRB2 (0.38) KMT2AMEN1NPC1PKMALDH1A1
SCHEMBL13370107 0.87 NR5A1 (0.45) THRB
SCHEMBL29492068 0.87 NR5A1 (0.45) THRB
SCHEMBL27729573 0.86 KDM4E (0.49) NPC1RAB9AALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285886-A Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2025-01-10 CN claimed
CN-113614581-B Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2024-10-25 CN claimed
CN-113045885-B Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2023-03-21 CN claimed
CN-114891336-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN claimed
CN-114891337-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN claimed
CN-114525027-A Transparent plastic base material and plastic lens 豪雅镜片泰国有限公司 2022-05-24 CN claimed
CN-119285886-A Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2025-01-10 CN disclosed
CN-113614581-B Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2024-10-25 CN disclosed
CN-118550104-A Spectacle lens and spectacles 豪雅镜片泰国有限公司 2024-08-27 CN disclosed
CN-113045885-B Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2023-03-21 CN disclosed
CN-114891336-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN disclosed
CN-114891337-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN disclosed
CN-114525027-A Transparent plastic base material and plastic lens 豪雅镜片泰国有限公司 2022-05-24 CN disclosed
CN-111149044-B Spectacle lens and spectacles 豪雅镜片泰国有限公司 2022-03-08 CN disclosed