Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721605 | 0.90 | KMT2A (0.56) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL29493433 | 0.88 | KMT2A (0.49) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL28722166 | 0.87 | NR1H2 (0.54) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL29493437 | 0.85 | LMNA (0.53) | MAPTALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL29597097 | 0.82 | MAPT (0.50) | MAPTALDH1A1KMT2ALMNAHPGD | |
| SCHEMBL29597503 | 0.82 | MAPT (0.53) | MAPTRAB9AALDH1A1KMT2ALMNA | |
| SCHEMBL28720781 | 0.80 | POLB (0.54) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL29596954 | 0.79 | POLB (0.60) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL28721606 | 0.76 | MAPT (0.46) | MAPTTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL29596624 | 0.75 | TP53 (0.53) | MAPTTSHRALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114411178-B | Polysubstituted pyrazole compound and electrochemical synthesis method thereof | 南京工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114411178-A | Polysubstituted pyrazole compound and electrochemical synthesis method thereof | 南京工业大学 | 2022-04-29 | — | — | CN | disclosed |