Phenopylate

Phenopylate

SCHEMBL29493743

O=C(Oc1ccc(Cl)cc1Cl)N1CCCC1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.62
HPGD P15428 4/20 0.61
TSHR P16473 3/20 0.61
GAA P10253 2/20 0.61
NPSR1 Q6W5P4 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
SMN1; SMN2 Q16637 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MAPT P10636 4/20 0.58
LMNA P02545 4/20 0.58
GLA P06280 1/20 0.58
MAPK1 P28482 1/20 0.58
ALOX12 P18054 1/20 0.57
TP53 P04637 3/20 0.54
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenopylate SCHEMBL10976218 1.00 HTT (0.62) HTTHPGDTSHRGAANPSR1
SCHEMBL16964920 0.89 SMN1; SMN2 (0.59) HTTHPGDTSHRGAANPSR1
SCHEMBL22372595 0.84 USP30 (0.60) HTTHPGDTSHRGAANPSR1
SCHEMBL13342914 0.84 SMN1; SMN2 (0.63) HTTHPGDTSHRGAANPSR1
SCHEMBL28788178 0.83 RECQL (0.63) HTTHPGDTSHRGAANPSR1
SCHEMBL22372601 0.83 USP30 (0.62) HTTHPGDTSHRGAANPSR1
SCHEMBL828934 0.81 MAPT (0.55) HTTHPGDTSHRGAANPSR1
SCHEMBL29372916 0.80 NPSR1 (0.66) HTTHPGDTSHRGAANPSR1
SCHEMBL19717911 0.80 NPSR1 (0.66) HTTHPGDTSHRGAANPSR1
SCHEMBL830223 0.80 TDP1 (0.57) HTTHPGDTSHRGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646332-A1 A ROTATING MEMBER FOR A VEHICLE AND A SUPPORTING STRUCTURE THEREOF TVS Motor Company Limited (IN) 2025-11-12 EP claimed
WO-2024147159-A1 A ROTATING MEMBER FOR A VEHICLE AND A SUPPORTING STRUCTURE THEREOF TVS MOTOR COMPANY LIMITED (IN) 2024-07-11 WO claimed
WO-2024109707-A1 FUSED RING PYRIDONE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF 合肥医工医药股份有限公司 2024-05-30 WO claimed
WO-2022143424-A1 POLYCYCLIC PYRIDONE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳市坤健创新药物研究院 2022-07-07 WO claimed
CN-109476709-B Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variants thereof FARMHANNONG Co.,Ltd. (KR) 2026-05-26 CN disclosed
WO-2026098491-A1 TRANSGENIC GLYCINE MAX EVENT KA-6G2Ø16-7 AND DETECTION METHOD THEREFOR 青岛清原种子科学有限公司 2026-05-15 WO disclosed
EP-4698033-A1 DEVICES, SYSTEMS, AND METHODS FOR PERFORMING A PROCEDURE WITH RESPECT TO TISSUE Boston Scientific Scimed, Inc. (US) 2026-02-25 EP disclosed
EP-4646332-A1 A ROTATING MEMBER FOR A VEHICLE AND A SUPPORTING STRUCTURE THEREOF TVS Motor Company Limited (IN) 2025-11-12 EP disclosed
WO-2025226838-A1 LIGATOR DEVICES AND SYSTEMS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-10-30 WO disclosed
WO-2024229441-A1 DEVICES, SYSTEMS, AND METHODS FOR PERFORMING A PROCEDURE WITH RESPECT TO TISSUE BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-11-07 WO disclosed
WO-2024178156-A2 IMPLANTABLE INTRACARDIAC ATRIAL RESTRAINING DEVICE AND SYSTEM FOR SENSING AND IDENTIFYING LOCATIONS OF CHANGES TO CARDIAC TISSUE THAT IMPACT ELECTRICAL SIGNALS THEREIN WOLF RANDALL K (US) 2024-08-29 WO disclosed
WO-2024147159-A1 A ROTATING MEMBER FOR A VEHICLE AND A SUPPORTING STRUCTURE THEREOF TVS MOTOR COMPANY LIMITED (IN) 2024-07-11 WO disclosed
WO-2024109707-A1 FUSED RING PYRIDONE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF 合肥医工医药股份有限公司 2024-05-30 WO disclosed
CN-111712567-B Compositions and methods for conferring and/or enhancing herbicide tolerance using protoporphyrinogen IX oxidase variants from cyanobacteria 福阿母韩农株式会社 2023-08-15 CN disclosed
EP-4221810-A1 FLOW RESTRICTING INTRAVASCULAR DEVICES FOR TREATING EDEMA White Swell Medical Ltd (IL) 2023-08-09 EP disclosed
CN-116064434-A Protoporphyrinogen oxidase variants 福阿母韩农株式会社 2023-05-05 CN disclosed
CN-109641940-B Protoporphyrinogen oxidase variants and methods and compositions for conferring and/or enhancing herbicide tolerance using the same 福阿母韩农株式会社 2022-11-18 CN disclosed
WO-2022143424-A1 POLYCYCLIC PYRIDONE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳市坤健创新药物研究院 2022-07-07 WO disclosed
WO-2022069944-A1 FLOW RESTRICTING INTRAVASCULAR DEVICES FOR TREATING EDEMA White Swell Medical Ltd (IL) 2022-04-07 WO disclosed
CN-114008196-A Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen IX oxidases of various cyanobacteria or variants thereof 福阿母韩农株式会社 2022-02-01 CN disclosed