Phenopylate

Phenopylate

SCHEMBL10976218

O=C(Oc1ccc(Cl)cc1Cl)N1CCCC1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.62
HPGD P15428 4/20 0.61
TSHR P16473 3/20 0.61
GAA P10253 2/20 0.61
NPSR1 Q6W5P4 3/20 0.58
TDP1 Q9NUW8 2/20 0.58
SMN1; SMN2 Q16637 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MAPT P10636 4/20 0.58
LMNA P02545 4/20 0.58
GLA P06280 1/20 0.58
MAPK1 P28482 1/20 0.58
ALOX12 P18054 1/20 0.57
TP53 P04637 3/20 0.54
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenopylate SCHEMBL29493743 1.00 HTT (0.62) HTTHPGDTSHRGAANPSR1
SCHEMBL16964920 0.89 SMN1; SMN2 (0.59) HTTHPGDTSHRGAANPSR1
SCHEMBL22372595 0.84 USP30 (0.60) HTTHPGDTSHRGAANPSR1
SCHEMBL13342914 0.84 SMN1; SMN2 (0.63) HTTHPGDTSHRGAANPSR1
SCHEMBL28788178 0.83 RECQL (0.63) HTTHPGDTSHRGAANPSR1
SCHEMBL22372601 0.83 USP30 (0.62) HTTHPGDTSHRGAANPSR1
SCHEMBL828934 0.81 MAPT (0.55) HTTHPGDTSHRGAANPSR1
SCHEMBL29372916 0.80 NPSR1 (0.66) HTTHPGDTSHRGAANPSR1
SCHEMBL19717911 0.80 NPSR1 (0.66) HTTHPGDTSHRGAANPSR1
SCHEMBL830223 0.80 TDP1 (0.57) HTTHPGDTSHRGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175004-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN IX OXIDASE OF VARIOUS CYANOBACTERIA OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2023-06-08 US claimed
US-11466286-B2 Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variant thereof Farmhannong Co., Ltd. (KR) 2022-10-11 US claimed
US-20220042033-A1 COMPOSITION AND METHOD FOR CONFERRING AND/OR ENHANCING TOLERANCE AGAINST HERBICIDES BY USING VARIANTS OF PPO Farmhannong Co., Ltd. (KR) 2022-02-10 US claimed
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 US disclosed
US-12635649-B2 Soybean line EC2020472 SYNGENTA CROP PROTECTION AG (CH) 2026-05-26 US disclosed
WO-2026098491-A1 TRANSGENIC GLYCINE MAX EVENT KA-6G2Ø16-7 AND DETECTION METHOD THEREFOR 青岛清原种子科学有限公司 2026-05-15 WO disclosed
US-12622398-B2 Soybean line EC2020188 SYNGENTA CROP PROTECTION AG (CH) 2026-05-12 US disclosed
US-20260117243-A1 Plants Having Increased Tolerance to Herbicides BASF AGRO BV (NL) 2026-04-30 US disclosed
US-20260101859-A1 SOYBEAN VARIETY SYNGENTA CROP PROTECTION AG (CH) 2026-04-16 US disclosed
US-12599085-B2 Soybean variety CL1945155 SYNGENTA CROP PROTECTION AG (CH) 2026-04-14 US disclosed
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2026-03-12 US disclosed
CN-109641940-A Proporphyrinogen oxidase variant and the method and composition that herbicide tolerant is assigned and/or enhanced using it 福阿母韩农株式会社 2019-04-16 CN disclosed
CN-109476709-A Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variants thereof 福阿母韩农株式会社 2019-03-15 CN disclosed
WO-2017217794-A1 PROTOPORPHYRINOGEN OXIDASE VARIANTS AND METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING THE SAME Farmhannong Co., Ltd. (KR) 2017-12-21 WO disclosed
WO-2017217793-A1 METHODS AND COMPOSITIONS FOR CONFERRING AND/OR ENHANCING HERBICIDE TOLERANCE USING PROTOPORPHYRINOGEN OXIDASE OR VARIANT THEREOF Farmhannong Co., Ltd. (KR) 2017-12-21 WO disclosed
EP-0078099-B1 SUBSTITUTED PHENYL (THIONO)CARBAMATES, HERBICIDAL COMPOSITIONS CONTAINING THE SAME AS ACIVE INGREDIENT AND METHOD OF CONTROLLING WEEDS KURARAY CO., LTD. (JP) 1985-11-27 EP disclosed
US-4521242-A Substituted phenyl carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-06-04 US disclosed
US-4491465-A Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1985-01-01 US disclosed
EP-0078099-A2 Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as acive ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1983-05-04 EP disclosed
EP-0065372-A1 Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1982-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599085-B2 Soybean variety CL1945155 CLK2, CLK1, CLK4 HTT 1909/4885HPGD 2813/4885TSHR 3533/4885
US-20260101859-A1 SOYBEAN VARIETY CLK2, CLK1, CLK3 HTT 2636/4885HPGD 3809/4885TSHR 2628/4885
US-12635649-B2 Soybean line EC2020472 CLK2, CLK1, CLK4 HTT 3017/4885HPGD 3856/4885TSHR 3098/4885
US-12637438-B2 Protoporphyrinogen oxidase inhibitors PPOX, CYP4X1, CBR3 HTT 3369/4885HPGD 387/4885TSHR 1818/4885
US-12622398-B2 Soybean line EC2020188 LPCAT1, PEX14, PLTP HTT 1972/4885HPGD 2798/4885TSHR 4303/4885
US-20260068883-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS PPOX, CYC1, CBR3 HTT 2850/4885HPGD 472/4885TSHR 2410/4885
US-20260117243-A1 Plants Having Increased Tolerance to Herbicides PPOX, PNPO, CYP4X1 HTT 3343/4885HPGD 454/4885TSHR 2844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.