Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | P2RX3 | P56373 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.86 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.86 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.86 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.86 |
| ▸ | CASP1 | P29466 | 1/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.86 |
| ▸ | RAB9A | P51151 | 1/20 | 0.86 |
| ▸ | CASP7 | P55210 | 1/20 | 0.86 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoppads SCHEMBL14702227 | 1.00 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL7196930 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL13624677 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL5287746 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL29357199 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL7196945 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL31236767 | 0.93 | MAPT (1.00) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL29374112 | 0.88 | MAPT (0.78) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL16450980 | 0.87 | MAPT (0.79) | MAPTTDP1P2RX3KDM4EP2RX2 | |
| SCHEMBL14506104 | 0.86 | MAPT (0.75) | MAPTTDP1P2RX3KDM4EP2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-11376269-B2 | Pharmaceutical compositions for the treatment of chemoresistant acute myeloid leukemia (AML) | INSERM (FR) | 2022-07-05 | — | — | US | disclosed |
| EP-3744348-B1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CHEMORESISTANT ACUTE MYELOID LEUKEMIA (AML) | INST NAT SANTE RECH MED (FR) | 2022-03-23 | — | — | EP | disclosed |