Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.43 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495255 | 0.82 | GRIA1 (0.43) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14543031 | 0.82 | GRIA1 (0.43) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29990313 | 0.82 | MAPT (0.41) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14653963 | 0.77 | KDM4E (0.37) | MAPTCYP3A4TDP1ALDH1A1KDM4E | |
| SCHEMBL27402973 | 0.76 | CYP3A4 (0.51) | MAPTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7979916 | 0.73 | GRIK1 (0.56) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1839319 | 0.73 | HPGD (0.51) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL1128949 | 0.73 | KDM4E (0.44) | MAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL8191290 | 0.73 | LMNA (0.43) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29495215 | 0.73 | CYP3A4 (0.46) | MAPTCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2026-03-19 | — | — | US | disclosed |
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, CD22, CD79B | MAPT 4832/4885GRIA1 1294/4885GRIA2 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.