Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 12/20 | 0.60 |
| ▸ | IKBKB | O14920 | 6/20 | 0.46 |
| ▸ | CHUK | O15111 | 6/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938328 | 1.00 | CD38 (0.60) | CD38IKBKBCHUKCDK8CYP11B1 | |
| SCHEMBL29495213 | 0.85 | CD38 (0.54) | CD38IKBKBCHUK | |
| SCHEMBL23306003 | 0.81 | CD38 (0.62) | CD38 | |
| SCHEMBL29495250 | 0.81 | CD38 (0.60) | CD38 | |
| SCHEMBL28723076 | 0.81 | CD38 (0.60) | CD38 | |
| SCHEMBL31036800 | 0.80 | CD38 (0.82) | CD38 | |
| SCHEMBL31266736 | 0.78 | MEN1 (0.46) | CD38 | |
| SCHEMBL28722350 | 0.78 | CD38 (0.46) | CD38 | |
| SCHEMBL29495224 | 0.78 | CD38 (0.46) | CD38 | |
| SCHEMBL22936248 | 0.77 | CD38 (0.71) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |