Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 17/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28723076 | 1.00 | CD38 (0.60) | CD38KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29495216 | 0.86 | CD38 (0.56) | CD38WNT1GSK3BDYRK1AMAP4K1 | |
| SCHEMBL28722350 | 0.82 | CD38 (0.46) | CD38 | |
| SCHEMBL29495224 | 0.82 | CD38 (0.46) | CD38 | |
| SCHEMBL28938328 | 0.81 | CD38 (0.60) | CD38 | |
| SCHEMBL29495183 | 0.81 | CD38 (0.60) | CD38 | |
| SCHEMBL22947225 | 0.76 | CD38 (1.00) | CD38 | |
| SCHEMBL28723030 | 0.76 | CD38 (1.00) | CD38 | |
| SCHEMBL31266736 | 0.76 | MEN1 (0.46) | CD38KDM4EMEN1MAPTKMT2A | |
| SCHEMBL31484633 | 0.73 | CD38 (0.45) | CD38WNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |