Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 8/20 | 0.41 |
| ▸ | DHODH | Q02127 | 10/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29495224 | 0.87 | CD38 (0.46) | CD38 | |
| SCHEMBL28722350 | 0.87 | CD38 (0.46) | CD38 | |
| SCHEMBL29495216 | 0.81 | CD38 (0.56) | CD38DHODH | |
| SCHEMBL22933157 | 0.80 | CD38 (0.55) | CD38 | |
| SCHEMBL21974418 | 0.76 | DHODH (0.60) | DHODHHSP90AA1ESR2TDP1 | |
| SCHEMBL29495213 | 0.74 | CD38 (0.54) | CD38 | |
| SCHEMBL22933156 | 0.73 | CD38 (0.78) | CD38 | |
| SCHEMBL28722981 | 0.73 | CD38 (0.78) | CD38 | |
| SCHEMBL27185599 | 0.70 | HSP90AA1 (0.41) | DHODHHSP90AA1ESR2TDP1 | |
| SCHEMBL2658150 | 0.69 | KDM4E (0.46) | DHODHHSP90AA1ESR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |