Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 14/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22933156 | 0.85 | CD38 (0.78) | CD38 | |
| SCHEMBL28722981 | 0.85 | CD38 (0.78) | CD38 | |
| SCHEMBL22933155 | 0.82 | CD38 (0.53) | CD38IRAK4 | |
| SCHEMBL22936248 | 0.80 | CD38 (0.71) | CD38 | |
| SCHEMBL29495257 | 0.80 | CD38 (0.41) | CD38 | |
| SCHEMBL28722350 | 0.79 | CD38 (0.46) | CD38 | |
| SCHEMBL29495224 | 0.79 | CD38 (0.46) | CD38 | |
| SCHEMBL23329529 | 0.74 | CD38 (0.56) | CD38IRAK4 | |
| SCHEMBL23304751 | 0.74 | CD38 (0.85) | CD38HTTALDH1A1 | |
| SCHEMBL22932654 | 0.74 | CD38 (0.71) | CD38KDM4ETSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021986-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | RIBON THERAPEUTICS, INC. (US) | 2021-02-04 | — | — | WO | disclosed |