Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 8/20 | 0.37 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969558 | 1.00 | USP7 (0.37) | USP7RENGABRPGABRDGABRA1 | |
| SCHEMBL29495868 | 0.88 | REN (0.37) | USP7RENGABRPGABRDGABRA1 | |
| SCHEMBL22969255 | 0.88 | REN (0.37) | USP7RENGABRPGABRDGABRA1 | |
| SCHEMBL22969636 | 0.86 | REN (0.38) | RENGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29495806 | 0.86 | REN (0.38) | RENGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22969494 | 0.81 | REN (0.37) | RENGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29495793 | 0.81 | REN (0.37) | RENGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22969282 | 0.81 | REN (0.37) | USP7RENGABRPGABRDGABRA1 | |
| SCHEMBL22969167 | 0.74 | REN (0.40) | USP7RENGABRPGABRDGABRA1 | |
| SCHEMBL29495843 | 0.74 | REN (0.40) | USP7RENGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |