Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27993085 | 0.98 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL14654316 | 0.82 | CYP1A2 (0.62) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL1545342 | 0.82 | CYP1A2 (0.68) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL7690167 | 0.82 | KDM4E (0.46) | ALDH1A1TDP1APPLMNAKDM4E | |
| SCHEMBL294802 | 0.80 | CYP1A2 (0.66) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL29708563 | 0.80 | CYP1A2 (0.72) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL8569016 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL864648 | 0.80 | CYP1A2 (0.72) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| SCHEMBL10387995 | 0.78 | CYP1A2 (0.76) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B | |
| Potassium SCHEMBL30586884 | 0.78 | CYP1A2 (0.69) | ALDH1A1CYP1A2CYP2C19CYP2C9ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744311-A | Synthesis method of bifenazate | MAISON CHEMICAL CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-103613600-A | Anilino podophyllotoxin derivative with anti-tumor activity and preparation method and application thereof | UNIV HUBEI TECHNOLOGY | 2014-03-05 | — | — | CN | claimed |
| US-3989756-A | RANEY CATALYST, DEHALOGENATION INHIBITOR | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1976-11-02 | — | — | US | claimed |
| CN-106573918-A | Azepanyl derivatives having antiparasitic activity and pharmaceutical compositions containing them | 默克专利股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-103328477-B | Pharmaceutical composition containing Pyridione derivatives | SK BIOPHARMACEUTICALS CO.,LTD. (KR) | 2016-01-20 | — | — | CN | disclosed |
| CN-105209444-A | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| CN-105189456-A | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC | 2015-12-23 | — | — | CN | disclosed |
| CN-102731382-B | 6-(polysubstituted aryl)-4-aminopyridine manthanoate and the purposes as weedicide thereof | THE DOW AGROSCIENCES, LLC. (US) | 2015-09-02 | — | — | CN | disclosed |
| CN-104884432-A | Alpha7 nicotinic acetylcholine receptor modulators and uses thereof-I | MERCK SHARP & DOHME | 2015-09-02 | — | — | CN | disclosed |
| CN-103796986-B | The preparation method of nitrobenzene compound | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2015-08-19 | — | — | CN | disclosed |
| CN-104781252-A | Alkyl-amide substituted pyridine compounds useful as IL-12, IL-23 and/or IFN alpha response modulators | BRISTOL MYERS SQUIBB CO | 2015-07-15 | — | — | CN | disclosed |
| WO-2005105927-A1 | PROCESS FOR PRODUCING HIGH-PURITY AZO DYES | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005105928-A1 | HIGH-PURITY NAPHTHOL AS PIGMENTS | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
| CN-1620442-A | five-membered ring compound | SUMITOMO PHARMA (JP) | 2005-05-25 | — | — | CN | disclosed |
| CN-1449391-A | N- (3, 5-dichloro-2-methoxyphenyl) -4-methoxy-3-piperazin-1-yl-benzenesulfonamide | SMITHKLINE BEECHAM PLC (GB) | 2003-10-15 | — | — | CN | disclosed |
| CN-1029958-C | Malonic acid derivative applied to hold back plant growth | UNION CARBIDE AGRICULT (US) | 1995-10-11 | — | — | CN | disclosed |
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |
| CN-87103552-A | Adopt malonate derivative to improve crop yield | — | 1988-07-06 | — | — | CN | disclosed |
| CN-87103683-A | Use of malonic acid derivatives for retarding plant growth | — | 1988-05-11 | — | — | CN | disclosed |
| US-3947247-A | STABILIZER COMPOSITION FOR DYESTUFFS | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 1976-03-30 | — | — | US | disclosed |